Release 450 is an 'Optimal Drivers for Enterprise' (ODE) branch release. ODE branches are
designed and tested to provide long-term stability and availability, making drivers from these branches ideal for enterprise customers and other users requiring application and hardware certification.

Quadro ODE drivers are a superset of the NVIDIA Studio Drivers and provide all the benefits of the Studio Driver, in addition to Quadro-specific enhancements and testing. 

What’s New in Version 450 U4

• Added security updates for driver components.
  See the NVIDIA Security Bulletin 5075 for details.

Fixed Issues in Version 450 U4

• [PTC Creo]: Models may get corrupted due to wrong VBO index buffer used.
• [OptiX][Quadro RTX]: Performance degradation may occur with apps when using Optix.

Open Issues in Version 450 U4

• [Alchemist]: The application crashes when either changing the display resolution or switching to another display with a different resolution.
  
  
To workaround, avoid changing the resolution, or disconnecting from or connecting to an external display with the application opened.

If you would like to be notified of upcoming drivers for Windows, please subscribe here.

• Quadro Release Notes (v452.39)
• Control Panel User's Guide

Quadro RTX Series:

Quadro RTX 8000, Quadro RTX 6000, Quadro RTX 5000, Quadro RTX 4000, Quadro RTX 3000

Quadro RTX Series (Notebooks):

Quadro RTX 5000, Quadro RTX 4000, Quadro RTX 3000

Quadro Series:

Quadro GV100, Quadro GP100, Quadro P6000, Quadro P5200, Quadro P5000, Quadro P4000, Quadro P2200, Quadro P2000, Quadro P1000, Quadro P620, Quadro P600, Quadro P400, Quadro M6000 24GB, Quadro M6000, Quadro M5000, Quadro M4000, Quadro M2000, Quadro K6000, Quadro K5200, Quadro K5000, Quadro K4000, Quadro K4200, Quadro K2200, Quadro K2000, Quadro K2000D, Quadro K1200, Quadro K620, Quadro K600, Quadro K420, Quadro 410

Quadro Series (Notebooks):

Quadro T2000, Quadro T1000, Quadro P5200, Quadro P5000, Quadro P4200, Quadro P3200, Quadro P4000, Quadro P3000, Quadro P2000, Quadro P1000, Quadro P600, Quadro P520, Quadro P500, Quadro M2200, Quadro M1200, Quadro M620, Quadro M520, Quadro M5500, Quadro M5000M, Quadro M4000M, Quadro M3000M, Quadro M2000M, Quadro M1000M, Quadro M600M, Quadro M500M, Quadro K2200M, Quadro K620M

Quadro Blade/Embedded Series :

Quadro RTX 5000, Quadro RTX 3000, Quadro T1000, Quadro P5000, Quadro P3000, Quadro P2000, Quadro P1000, Quadro M5000 SE, Quadro M3000 SE

Quadro NVS Series:

NVS 810, NVS 510

Quadro Sync Series:

Quadro Sync II, Quadro Sync

NVS Series:

NVS 810, NVS 510