In the healthcare industry, gathering insights from real-world data is becoming essential for improving clinical trial processes and overall system efficiency. AI tools can enhance this by evaluating large volumes of available data on clinical trials. Examples of applications include screening of clinical trial participants and identifying eligible individuals faster. It can also integrate diverse data types for comprehensive analysis, enabling patient-trial matching. AI-driven cohort audit analysis helps ensure the integrity of study group compositions, while generative AI can support second opinions by providing expert-level evaluations based on vast medical knowledge. Additionally, AI enhances disease and symptom search functionalities, supported pandemic response efforts, and helps maintain financial integrity by optimizing revenue cycle management.